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New Antidepressant Developments and Approvals
New antidepressant development, until fairly recently, was at best a random, and at worst a problematic and frustrating, process. Often, medications that were developed for one thing were discovered quite accidentally to have much more important therapeutic effects for a completely different disorder. It has been well described that some of the original antipsychotics were originally developed to assist in anesthesia, and some of the original new antidepressants were originally intended to be medications for tuberculosis or psychosis. New antidepressant development was done on a "chemical" basis; that is, guesses were made as to compounds that would be safe and effective based on chemical structures of established medications. This was very much a trial-and-error process, since very little was known about how these drugs worked and very little could be measured beyond actually giving them to a patient. New antidepressant development always has been and always will be a partnership between efficacy (ie, whether the drug is effective) and safety (ie, whether the drug can be tolerated by a patient). There were very few ways of knowing the answers to those two questions about any given compound unless you tried it, a process not without its obvious risks. It should be noted that vagus nerve stimulation for depression clearly meets the two main FDA requirements of safety and efficacy. Medications to treat depression; mild, severe, bipolar, or treatment-resistant, make the news most frequently, and deservedly so. Their progress and approval can potentially benefit almost 8 million Americans who suffer from some form of depression. Because there seems to be more frequency now of depression that is treatment-resistant, meaning most methods of treatment (medications, psychotherapy, electroconvulsive therapy, or a combination of more than one treatment) have failed for a patient, the approval of new antidepressants from companies like Merck, Lilly, and Pfizer, are more important than ever. This is because a new class of medication for treating depression has not been developed in over a decade. On July 18th, 2005 the FDA approved the first ever treatment long term treatment option for depression; vagus nerve stimulation. You can learn more about this remarkable treatment at http://www.VagusNerveStimulator.com There is a free electronic newsletter to keep you up-to-date. Charles Donovan was a patient in the FDA investigational trial of vagus nerve stimulation as a treatment for chronic or recurrent treatment-resistant depression. He was implanted with the vagus nerve stimulator in April of 2001. He chronicles his journey from the grips of depression thanks to vagus nerve stimulation therapy in his book: Out of the Black Hole: The Patient's Guide to Vagus Nerve Stimulation and Depression The book was exhibited at the American Psychiatric Association's Annual Meeting in May. It is available on his web site and 24 hours a day/7 days a week through the toll free number 1-888-VAGUS-88. If you use discount code FDAYES(all caps), it will save you 25% off the cost of the book and you will get automatic free shipping via U.S. Postal Priority Mail. The book is also available through Amazon.com and Barnes & Noble.com. The discount does not apply at these two sites. He is the founder of the http://www.VagusNerveStimulator.com Web Site
Latest News:Site: Yahoo! News Search Results for news News 8 Red Cross blood drive in Orange News 8 and the Red Cross are teaming up again today for a 'Remembering 9/11 Blood Drive'. News Near You for Sept. 10 NEWS NEAR YOU HanoverThe annual winterization program in Hanover County is accepting applications from low-income, elderly or disabled homeowners and volunteers who want to help them. News by location Get local and national news updates via E-mail. Duke University School of Nursing will offer several graduate courses in Fayetteville in 2011. Participants will meet once a month at the Southern Regional Area Health Education Center at 1601 Owen Drive. Each course will involve online learning. News media giants tap new media to stay alive Traditional news media outlets are staving off their much-reported impending demise by learning to use the very social media tools that are supposedly clobbering them to death. News 8 Follows First-Year Teacher Throughout the school year, News 8 will follow Darryl Wende during his first year of teaching in a series of reports called "Making the Grade." News by location Get local and national news updates via E-mail. A small fire that someone set on a street in west Fayetteville may have been a ploy to get inside homes in the neighborhood, police said. News by location Get local and national news updates via E-mail. An investigator with the Consumer Product Safety Commission was at Fort Bragg on Thursday conducting tests inside a military home where three families were staying at different times before their babies died mysteriously. News Animation Goes Political: Knocks Pres. Obama Speech In New Video The Taiwanese NMA News animation videos are coming out with increasing regularity , and are getting more timely and news-worthy . In the past, they've been fairly fun in their bipartisan ribbing toward both political parties - but their latest Pres. Barack Obama video takes some sharp jabs at the Commander-in-Chief. News by location Get local and national news updates via E-mail. You had to feel good about how the rest of the state of North Carolina felt about Fayetteville and Cumberland County football this week as reflected in the first Associated Press high school polls. News by location Get local and national news updates via E-mail. Two men are accused of robbing a pizza delivery driver at gunpoint Wednesday night, off Rosehill Road. Site: news - Google News Adobe, Google on Apple's App Store Changes: 'great News' - PC World
MORE RESOURCES: Site: Yahoo! News Search Results for medicine Medicine to be taught at IIT, says Sibal Union Human Resource and Development (HRD) Minister Kapil Sibal on Friday said the Indian Institute of Technology (IITs) across the country will soon introduce new courses in medicine and even enroll foreign students as well as recruit foreign faculties at the post graduate level. Medicine to be taught at IIT: Kapil Sibal Already the premier institute for Technology, the Indian Institute of Technology (IIT) may soon be producing top of the line doctors as well. The HRD Ministry has decided that medicine will be taught at the IITs, to facilitate research across disciplines. Medicine Lodge teen killed in auto accident A one-vehicle accident in Barber County has claimed the life of a Medicine Lodge teenager and injured three others. BG Medicine's Losses Mount As It Negotiates FDA Marketing Approval BG Medicine's Losses Mount As It Negotiates FDA Marketing Approval Defensive Medicine Costs Much Less Than 'Imagined' By Malpractice Reformists The combined cost of malpractice -- and doctors' efforts to avoid it by practicing so-called defensive medicine -- costs about $55.6 billion a year, or 2.4 percent of total health spending, according to a new analysis by "Harvard University's Atul Gawande and co-authors, Bloomberg reports. "The yearly price of so-called defensive medicine -- tests, visits and procedures performed to reduce ... Roche Experimental Cancer Medicine Shows Promise Against Resistant Tumors An experimental medicine being developed by Roche Holding AG ?s Genentech unit may help a common chemotherapy drug kill cancer cells that are otherwise resistant to treatment, a study found. How Do Sport Medicine Doctors Make Return-to-Play Decisions? When is it appropriate for an injured athlete to return to competition? A new three-step framework provides team physicians and other sport medicine clinicians with guidance on making complex decisions about return to play, reported in the September Clinical Journal of Sport Medicine. Morehouse School of Medicine Selects SunGards Banner Digital Campus, Offsite Hosting and Rapid Implementation Services ... MALVERN, Pa., September 9, 2010 Morehouse School of Medicine MSM is implementing SunGard Higher Educations Banner Digital Campus to help provide student services that mirror the quality of the institutions medical program and help the school retain its competitive edge. MSM also contracted with SunGard Higher Education for offsite hosting and application management to help keep its new... First NY Professional Sleep Medicine Conference To Be Held In Albany, NY Oct. 1-2, 2010 The New York State Society of Sleep Medicine (NYSSSM) will hold its first annual meeting and sleep conference, featuring speakers who are nationally recognized experts in clinical sleep medicine, on October 1-2, 2010 in Albany, NY. Among the topics at the two-day conference for physicians, psychologists, dentists and technologists are: - "Recent Advances in the Treatment of Excessive Sleepiness ... Cough medicine ingredient may treat prostate cancer Noscapine, a natural substance found in cough medicine, may prove useful in treating advanced prostate cancer, according to studies in mice. Site: medicine - Google News College of Human Medicine transforms medical education with new Secchia Center - MSU News
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